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Organization of peptidoglycan synthesis in nodes and separate rings at different stages of cell division in Streptococcus pneumoniae
Perez, A. J.; Boersma, M. J.; Bruce, K. E.; Lamanna, M. M.; Shaw, S. L.; Tsui, H.-C. T.; Taguchi, A. Carlson, E. E.; VanNieuwenhze, M. S.; Winkler, M. E., Mol. Microbiol. 2020,00:1–18
A Division of Labor in the Recruitment and Topological Organization of a Bacterial Morphogenic Complex
Caccamo, P. D.; Jacq, M.; VanNieuwenhze, M. S.; Brun, Y. V., Curr. Biol. 2020, 30, 3908-3922.
The Pneumococcal Iron Uptake Protein A (PiuA) Specifically Recognizes Tetradentate Fe(III)bis- and Mono-Catechol Complexes
Zhang, Y.; Edmonds, K. A.; Raines, D. J.; Murphy B. A.; Wu, H.; Guo, C.; Nolan, E. M.; VanNieuwenhze, M. S.; Duhme-Klair, A.-K.; Giedroc, D. P., J. Mol. Biol. 2020, 432, 5390-5410.
Synthesis of 9-Dechlorochrysophaentin A Enables Studies Revealing Bacterial Cell Wall Biosynthesis Inhibition Phenotype in B. subtilis
Fullenkamp, C.; Hsu, Y.-P.; Quardokus, E.; Zhao, G.; Bewley, C.; VanNieuwenhze, M.; Sulikowski, G., J. Am. Chem. Soc. 2020, 142, 16161-16166.
Non-walled spherical Acinetobacter baumannii is an important type of persister upon b-lactam antibiotic treatment
Zou, J.; Xie, R. R.; VanNieuwenhze, M. S.; Peng, B.; Zheng, J., Emerg. Microbes Infect. 2020, 9(1), 1149-1159.
Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum
Sogues, A.; Martinez, M.; Gaday, Q.; Ben-Assaya, M.; Graña, M.; Voegele, A.; VanNieuwenhze, M.; England, P.; Haouz, A.; Chenal, A.; Trépout, S.; Duran, R.; Wehenkel, A. M.; Alzari, P., Nat. Commun. 2020, 11, 1641.
Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodeling
Culp, E. J.; Waglechner, N.; Wang, W.; Fiebig-Comyn, A. A.; Hsu, Y. P.; Koteva, K.; Sychantha, D.; Coombes, B. K.; Van Nieuwenhze, M. S.; Brun, Y. V.; Wright, G. D., Nature 2020, 578, 582-587.
Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori
Taylor, J. A.; Bratton, B. P.; Sichel, S. R.; Blair, K. M.; Jacobs, H. M.; DeMeester, K. E.; Kuru, E.; Gray, J.; Biboy, J.; VanNieuwenhze, M. S.; Vollmer, W.; Grimes, C. L.; Shaevitz, J. W.; Salama, N. R., Elife 2020, 9.
D‐Amino Acid Derivatives as in Situ Probes for Visualizing Bacterial Peptidoglycan Biosynthesis
Hsu, Y. P.; Booher, G.; Egan, A.; Vollmer, W.; VanNieuwenhze, M. S., Acc. Chem. Res. 2019, 52, 2713-2722.
Mechanisms of Incorporation for D‐Amino Acid Probes That Target Peptidoglycan Biosynthesis
Kuru, E.; Radkov, A.; Meng, X.; Egan, A.; Alvarez, L.; Dowson, A.; Booher, G.; Breukink, E.; Roper, D. I.; Cava, F.; Vollmer, W.; Brun, Y.; VanNieuwenhze, M. S., ACS Chem Biol 2019, 14, 2745-2756.
SEDS-bPBP pairs direct lateral and septal peptidoglycan in Staphylococcus aureus
Reichmann, N. T.; Tavares, A. C.; Saraiva, B. M.; Jousselin, A.; Reed, P.; Pereira, A. R.; Monteiro, J. M.; Sobral, R. G.; VanNieuwenhze, M. S.; Fernandes, F.; Pinho, M. G., Nat. Microbiol. 2019, 4, 1368-1377.
Spheroplast-Mediated Carbapenem Tolerance in Gram-Negative Pathogens
Cross, T; Ransegnola, B.; Shin, J.-H.; Weaver, A.; Fauntleroy, K.; VanNieuwenhze, M.; Westblade, L. F.; Dörr, T. Antimicrob. Agents Chemother. 2019, 63(9): e00756-19.
Optimized Protocol for the Incorporation of FDAA (HADA Labeling) for in situLabeling of Peptidoglycan
Pazos, K.; Pazos, M.; VanNieuwenhze, M. S.; Vollmer W., Bio. Protoc. 2019, 9(15).
Expedient and scalable synthesis of orthogonally-protected ß-methyllanthionines by indium(III)-mediated ring-opening of aziridines
Li, Z.; Gentry, Z.; Murphy, B.; VanNieuwenhze, M. S., Org. Lett. 2019, 21, 2200-2203.
Fluorogenic D-amino acids enable real-time monitoring of peptidoglycan biosynthesis and high-throughput transpeptidation assays
Hsu, Y.-P.; Hall, E.; Booher, G.; Murphy, B.; Radkov, A. D.; Yablonowski, J.; Mulcahey, C.; Alvarez Munoz, L.; Cava, F.; Brun, Y. V.; Kuru, E.; VanNieuwenhze, M. S., Nat. Chem. 2019, 11, 335-341.
Studies toward the Total Synthesis of Nogalamycin: Construction of the Complete ABCDEF-ring System via a Convergent Hauser Annulation
Peng, R.; VanNieuwenhze, M. S., J. Org. Chem. 2019, 84, 760-768.
Construction of the DEF-Benzoxocin Ring System of Nogalamycin and Menogaril via a Reductive Heck Cyclization
Peng, R.; VanNieuwenhze, M. S., J. Org. Chem.2019, 84, 173-180.
An Acinetobacter baumannii zinc-regulated peptidase maintains cell wall integrity during immune-mediated nutrient sequestration
Lonergan. Z. R.; Nairn, B. L.; Hsu, Y.-P.; Wang, J.; Hesse, L. E.; Beavers, W. N.; Chazin, W. J.; VanNieuwenhze, M. S.; Giedroc, D. P.; Skaar, E. P., Cell Reports 2018, 26(8), P2009-2018.E6.
Use of a Fluorescent Analogue of a HBV Core Protein-directed Drug to Interrogate an Antiviral Mechanism
Nair, S.; Li, L.; Francis, S.; Turner, W.; VanNieuwenhze, M.; Zlotnick, A., J. Am. Chem. Soc. 2018, 140, 15261-15269.
The fluorescent D-amino acid NADA as a tool to study the conditional activity of transpeptidases in Escherichia coli
Silva, A. M.; Otten, C.; Biboy, J.; Breukink, E.; VanNieuwenhze, M. S.; Vollmer, W.; den Blaauwen, T., Front. Microbiol. 2018, 9:2101.
Genetic determinants of penicillin tolerance in Vibrio cholerae
Weaver, A. I.; Murphy, S. G.; Umans, B.; Tallavajhala ,S.; Onyekwere, I.; Deibold, P.; Wittels, S.; Shin, J.-H.; VanNieuwenhze, M. S.; Waldor, M. K.; Dörr, T., Antimicrob. Agents Chemother. 2018, 62 (10): e01326-18.
Copper inhibits peptidoglycan LD-transpeptidase suppressing ß-lactam resistance due to by-pass of penicillin-binding proteins
Peters, K.; Pazos, M.; Edoo, Z.; Hugonnet, J.-E.; Martorana, A. M.; Polissi, A.; VanNieuwenhze, M. S.; Arthur, M.; Vollmer, W., Proc. Natl. Acad. Sci, USA, 2018, 115 (42), 10786-10791.
Coupling of polymerase and carrier lipid phosphatase prevents product inhibition in peptidoglycan biosynthesis
Hernádez-Rocamora, V.; Otten, C.; Radkov, A.; Simorre, J.-P.; Breukink, E.; VanNieuwenhze, M. S.; Vollmer, W., The Cell Surface 2018, 2, 1-13.
Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division
Pazos, M.; Peters, K.; Casanova, M.; Palacios, P.; VanNieuwenhze, M. S.; Breukink, E.; Vicente, M.; Vollmer, W., Nat. Commun. 2018, 9, 5090.
An assembly-activating site in the Hepatitus B virus capsid protein can also trigger disassembly
Qazi, S. A.; Schlicksup, C. J.; Rittichier, J.; VanNieuwenhze, M.; Zlotnick, A., ACS Chem. Biol. 2018, 13, 2114-2120.
Hepatitis B virus core protein allosteric modulators can distort and disrupt intact capsids
Schlicksup, C. J.; Wang, J. C.-Y.; Francis, S.; Venkatakrishnan, B.; Turner, W. W.; VanNieuwenhze, M. S.; Zlotnick, A., eLife 2018; 7:e31473.
Peptidoglycan synthesis drives cytokinesis independent of FtsZ treadmilling
Monteiro, J. M.; Periera, A. R.; Reichmann, N. T.; Saraiva, B. M.; Fernandes, P. B.; Veiga, H.; Tavares, A. C.; Santos, M.; Ferreira, M. T.; Macário, V.; VanNieuwenhze, M. S.; Filipe, S. R.; Pinho, M., Nature 2018, 554, 528-532.
The cell wall hydrolase Pmp23 safeguards the division ring in Streptococcus pneumoniae
Morlot, C; Jacq, M.; Arthaud, C.; Manuse, S.; Bellard, L.; Peters, K.; Gallet, B.; Galindo, J.; Doan, T.; Vollmer, W.; Brun, Y. V.; VanNieuwenhze, M. S.; DiGuilmi, A.-M.; Vernet, T.; Grangeasse, C., Sci. Rep.-UK 2018, 8, 7591.
Host-Polarized Cell Growth in Animal Symbionts
Pende, N.; Wang, J.; Weber, P. M.; Verheul, J.; Kuru, E.; Rittmann, S. K. M. R.; Leisch, N.; VanNieuwenhze, M. S.; Brun, Y. V.; den Blaauwen, T.; Bulgheresi, S., Curr. Biol. 2018, 28, 1039-1051.e5.
- Research Highlight: Thanbichler, M., “Cell Division: “Symbiotic Bacteria Turn It Upside Down,” Curr. Biol. 2017, 28, R306.
Peptidoglycan O-acetylation is functionally related to cell wall biosynthesis and cell division in Streptococcus pneumoniae
Bonnet, J.; Durmont, C.; Jacq, M.; Mortier-Barrière, I.; Campo, N.; VanNieuwenhze, M. S.; Brun, Y.; Arthaud, C.; Gallet, B.; Moriscot, C.; Morlot, C.; Vernet, T.; DiGuilmi, A. M., Mol. Microbiol. 2017, 106 (5) 832-846.
Full color palette of fluorescent D-amino acids for in situ labeling of bacterial cell walls
Hsu, Y.-P.; Rittichier, J.; Kuru, E.; Yablonowski, J., Pasciak, E.; Tekkam, S.; Hall, E.; Murphy, B.; Lee, T. K.; Garner, E. C.; Huang, K. C.; Brun, Y. V.; VanNieuwenhze, M. S., Chem. Sci. 2017, 8, 6313-6321.
Construction of the DEF-Ring System of Nogalamycin and Menogaril via an Efficient Suzuki-Miyaura Reaction
Peng, R.; VanNieuwenhze, M. S., Tetrahedron Lett. 2017, 58, 2236-2239.
Fluorescent D-amino acids reveal bicellular cell wall modifications important for Bdellovibrio bacteriovorus predation including L,D-transpeptidase-mediated prey strengthening
Kuru, E.; Lambert, C.; Rittichier, J.; Till, R.; Ducret, A.; Derouaux, A.; Gray, J.; Biboy, J.; Vollmer, W.; VanNieuwenhze, M. S.; Brun, Y.; Sockett, R. E., Nat. Microbiol. 2017, 2, 1648-1657.
Evidence for a peptidoglycan-like structure in Orientia tsutsugamushi
Atwal, S.; Giengkam, S.; Chaemchuen, S.; Dorling, J.; Kosaisawe, D.; VanNieuwenhze, M.; Sampattavanich, S.; Schumann, P.; Salje, J., Mol. Microbiol. 2017, 105(3), 440-542.
A programmed cell division delay preserves genome integrity during natural genetic transformation in Streptococcus pneumoniae
Bergé, M. J.; Mercy, C.; VanNieuwenhze, M. S.; Brun, Y. V.; Grangeasse, C.; Polard, P.; Campo, N., Nat. Commun. 2017, 8, 1621.
Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division
Bisson-Filho, A. W.; Hsu, Y.-P.; Squyres, G. R.; Kuru, E.; Wu, F.; Jukes, C.; Dekker, C.; Holden, S.; VanNieuwenhze, M. S.; Brun, Y. V.; Garner, E. C., Science 2017, 355, 739-743.
- Research Highlight: “Treadmilling runs bacterial division,” Rev. Microbiol 2017, 15, 193. DOI: 10.1038/nrmicro.2017.24.
- Indiana University News Release: “IU researchers help add greater precision to fight against antibiotic-resistant bacteria,” February 16, 2017. URL: http://archive.news.indiana.edu/releases/iu/2017/02/superbug-cellular-division.shtml
A Periplasmic Polymer Curves Vibrio cholerae and Promotes Pathogenesis
Bartlett, T. M.; Bratton, B. P.; Miguel, A.; Duvshani, A.; Miguel, A.; Sheng, Y.; Martin, N. R.; Nguyen, J. P.; Persat, A.; Desmarais, S. M.; VanNieuwenhze, M. S.; Huang, K. C.; Zhu, J.; Shaevitz, J. W.; Gitai, Z., Cell 2017, 168, 172-185.
Dual mode of action for plusbacin A3 in Staphylococcus aureus
O’Connor, R. D.; Singh, M.; Chang, J.; Kim, S. J.; VanNieuwenhze, M. S.; Schaefer, J., J. Phys. Chem. B. 2017, 121, 1499-1505.
Live imaging of the genetically intractable obligate intracellular bacteria Orientia tsutsugamushi using a panel of fluorescent dyes
Atwal, S.; Giengkam, S.; VanNieuwenhze, M.; Salje, J., J. Microbiol. Meth. 2016, 130, 169-176.
Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and ß-lactam resistance in Escherichia coli
Huggonet, J.-E.; Mengin-Lecreulx, D.; Monton, A.; den Blaauwen, T.; Carbonelle, E.; Vexkerlé, C.; Brun, Y. V.; VanNieuwenhze, M.; Bouchier, C.; Tu, K.; Rice, L. B.; Arthur, M., eLife 2016; 5:319469.
The mechanism of force transmission at bacterial focal adhesion complexes
Faure, L.; Fiche, J.-B.; Espinosa, L.; Ducret, A.; Anantharaman, V.; Luciano, J.; Lhospice, S.; Islam, S.; Tréguier, J.; Sotes, M.; Kuru, E.; VanNieuwenhze, M.; Brun, Y.; Theodoly, O.; Aravind, L.; Nollmann, M., Mignot, T., Nature 2016, 539, 530-535.
Structure-function analysis of the extracellular domain of the pneumococcal cell division site positioning protein MapZ
Manuse, S.; Jean, N. L.; Guinot, M.; Lavergne, J.-P.; Laguri, C.; Bougault, C. M.; VanNieuwenhze, M. S; Grangeasse, C.; Simorre, J.-P., Nat. Commun. 2016, 7, 12071.
FtsZ-dependent elongation of a coccoid bacterium
Pereira, A. R.; Hsin, J.; Krol, E.; Tavares, A. C.; Flores, P.; Hoiczyk, E.; Ng, N.; Dalkovic, A.; VanNieuwenhze, M. S.; Brun, Y. V.; Roemer, T.; Carballido-Lopez, R.; Sheffers, D.-J.; Huang, K. C.; Pinho, M. G., mBio 2016, 7(5):e00908-16.
Pathogenic Chlamydia lack a ‘classical’ sacculus but synthesize a narrow, midcell peptidoglycan ring, regulated by MreB, for cell division
Liechti, G.; Kuru, E.; Packiam, M.; Rittichier, J. T.; Tekkam, S.; Hall, E.; Hsu, Y.-P.; VanNieuwenhze, M. S.; Brun, Y. V.; Maurelli, A. T., PLoS Pathog. 2016, 12(5):e1005590.
D-Alanine-Controlled Transient Intestinal Mono-Colonization with Non-Laboratory-Adapted Commensal E. coli Strain HS
Cuenca, M.; Pfister, S. P.; Buschor, S.; Bayramova, F.; Hernandez, S. B.; Cava, F.; Kuru, E.; VanNieuwenhze, M. S.; Brun, Y. V.; Coelho, F; Hapfelmaier, S., PLoS One 2016, 11(3):e0151872.
Minimal Peptidoglycan Turnover in Wild-Type and PG Hydrolase and Cell Division Mutants of Streptococcus pneumoniae D39 Growing Planktonically and in Host-Relevant Biofilms
Boersma, M. J.; Kuru, E.; Rittichier, J. T.; VanNieuwenhze, M. S.; Brun, Y. V.; Winkler, M. E., J. Bacteriol. 2015, 197, 3463-3471.
- Work featured on cover: J. Bacteriol. 2015, 197, 3463-3471
Cell shape dynamics during the Staphylococci cell cycle
Monteiro, J. M.; Fernandes, P. B.; Vaz, F.; Pereira, A. R.; Tavares, A. C.; Ferreira, M. T.; Kuru, E.; VanNieuwenhze, M.; Brun, Y. V.; Filipe, S. R.; Pinho, M. G., Nat. Commun. 2015, 6, 8055.
Annamox Planctomycetes have a peptidoglycan cell wall
van Teeseling, M. C. F.; Mesman, R. J.; Kuru, E.; Espaillat, A.; Cava, F.; Brun, Y. V.; VanNieuwenhze, M. S.; Kartal, B.; van Niftrik, L., Nat. Commun. 2015, 6, 6878.
Synthesis of fluorescent D-amino acids and their use for probing peptidoglycan synthesis and bacterial growth in situ
Kuru, E.; Tekkam, S.; Hall, E.; Brun, Y. V.; VanNieuwenhze, M. S., Nat. Protoc. 2015, 10, 33-52.
Electroreductive Dimerization of Coumarin and Coumarin Analogues at Carbon Cathodes
Pasciak, E. M.; Rittichier, J. R.; Chen, C.-H.; Mubarak, M.; VanNieuwenhze, M. S.; Peters, D. G., J. Org. Chem. 2015, 80, 274-280.
MapZ beacons the division sites and positions FtsZ-rings in Streptococcus pneumoniae
Fleurie, A.; Lesterlin, C.; Zhao, C.; Manuse, S.; Cluzel, C.; Campo, N.; Lavergne, J.-P.; Franz, M.; Macek, B.; Kuru, E.; VanNieuwenhze, M. S.; Brun, Y. V.; Sherratt, D.; Grangeasse, C., Nature 2014, 516, 259-262.
Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division of Streptococcus pneumonia D39
Tsui, H.-C. T.; Boersma, M. J.; Vella, S. A.; Kocaoglu, O.; Kuru, E.; Perceny, J. K.; Carlson, E. E.; VanNieuwenhze, M. S.; Brun, Y. V.; Shaw, S. L.; Winkler, M. E., Mol. Microbiol. 2014, 94 (1), 21-40.
- MicroCommentary: Cadby, I. T.; Lovering, A. L., “Molecular surveillance of the subtle septum: discovering a new mode of peptidoglycan synthesis in streptococci,”Mol. Microbiol. 2014, 94 (1), 1-4. DOI: 1111/mmi.12756.
- Work featured on cover: Mol. Microbiol. 2014, 94 (1); URL: http://onlinelibrary.wiley.com/store/10.1111/mmi.12795/asset/mmi12795.pdf?v=1&t=i0tsajk7&s=b4a6b9e49c66fe6455260ce6ae9da01b776b1f0a
Atheroprotective immunization with malondialdehyde modified LDL is hapten specific, dependent on advanced MDA-adducts: Implications for development of an atheroprotective vaccine
Gonen, A.; Hansen, L. F.; Turner, W. W.; Montano, E. N.; Que, X.; Rafia, A.; Chou, M.-Y.; Wiesner, P.; Tsiantoulas, D.; Corr, M.; VanNieuwenhze, M. S.; Tsimikas, S.; Binder, C. J.; Witztum, J. L.; Hartvigsen, K., J. Lipid Res. 2014, 55, 2137-2155.
Interplay of the serine/threonine kinase StkP and the paralogs DivIVA and GpsB in pneumococcal cell elongation and division
Fleurie, A.; Manuse, S; Zhao, C.; Campo, N.; Cluzel, C.; Lavergne, J.-P.; Freton, C.; Guiral, S.; Soufi, B.; Macek, B.; Kuru, E.; VanNieuwenhze, M. S., Brun, Y.; DiGuilmi, A.-M.; Claverys, J.-P.; Galinier, A.; Grangeasse, C., PLoS Genet. 2014, 10(4): e1004275.
A new metabolic cell wall labeling method reveals peptidoglycan in Chlamydia trachomatis
Liechti, G.; Kuru, E.; Hall, E.; Kalinda, A.; Brun, Y. V.; VanNieuwenhze, M. S.; Maurelli, A. T., Nature 2013, 506, 507-510.
- Research Highlight: Mohammadi, T.; Breukink, E., “The Chlamydial Anomaly Clarified?” ChemBioChem 2014, 15, 1391-1392.
- Research Highlight: Kåhrström, C. T., “Chlamydiae play by their own rules,” Rev. Microbiol. 2014, 12, 76-77.
- Highlighted by Faculty of 1000 Prime, January 27, 2014.
- Highlighted in, “Revealing Bacterial Building Blocks,” Inside Life Science, published online by the National Institute of General Medical Sciences, December 24, 2013. (http://publications.nigms.nih.gov/insidelifescience/holiday-season-cells.html)
- Highlighted in, “IU Researchers Solve Chlamydia Bacteria Mystery,” posted December 26, 2013. (http://indianapublicmedia.org/news/iu-researchers-solve-chlamydia-bacteria-mystery-60561/)
- Indiana University News Release: “IU-designed probe opens new path for drug development against leading STD,” December 11, 2013. URL: http://archive.news.indiana.edu/releases/iu/2013/12/cell-wall-labeling-peptidoglycan.shtml
Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ
Pilhofer, M.; Aistleitner, K.; Biboy, J.; Gray, J.; Kuru, E.; Hall, E.; Brun, Y. V.; VanNieuwenhze, M. S.; Vollmer, W.; Horn, M.; Jensen, G. J., Nat. Commun. 2013, 4, 2856.
Peptidoglycan transformations during Bacillus subtilis sporulation
Tocheva, E. I.; López-Garrido, J.; Hughes, H. V.; Fredlund, J.; Kuru, E.; VanNieuwenhze, M. S.; Brun, Y. V.; Pogliano, K.; Jensen, G. J., Mol. Microbiol. 2013, 88(9), 673-686.
Isotridecanyl Side Chain of Plusbacin A3 is Essential for the Transglycosylase Inhibition of Peptidoglycan Biosynthesis
Kim, S. J.; Singh, M.; Wohlrab, A.; Yu, T.-Y.; O’Connor, R. D.; VanNieuwenhze, M. S.; Schaefer, J., Biochemistry 2013, 52, 1973-1979.
In Situ Probing of Newly Synthesized Peptidoglycan in Live Bacteria with Fluorescent D-Amino Acids
Kuru, E.; Hughes, H. V.; Brown, P. J. B.; Hall, E.; Tekkam, S.; Cava, F.; de Pedro, M. A.; Brun, Y. V.; VanNieuwenhze, M. S., Angew. Chem. Int. Ed. 2012, 51, 12519-12523.
- Designated a ‘hot paper’ by the editors of Angewandte Chemie
- Inside cover highlight, Chem. Int. Ed. 2012, 51, 12378.
- Indiana University News Release: “Filming bacterial life in multicolor as a new diagnostic and antibiotic discovery tool,” October 9, 2012. URL: http://newsinfo.iu.edu/news-archive/23263.html.
- Highlighted in Eng. News 2012, 90 (43), 35.
- Research Highlight in Rev. Microbiol. 2012, 12, 802.
- Highlighted in NIGMS Biomedical Beat, November 15, 2012.
- “Bacterial Portrait Sessions,” on the PBS series, “A Moment of Science,” broadcast March 25, 2013.
- Sightings feature: “See How They Grow,” appeared in American Scientist, April 2013
In Situ Probing of Newly Synthesized Peptidoglycan in Live Bacteria with Fluorescent D-Amino Acids
Kuru, E.; Hughes, H. V.; Brown, P. J. B.; Hall, E.; Tekkam, S.; Cava, F.; de Pedro, M. A.; Brun, Y. V.; VanNieuwenhze, M. S., Angew. Chem. 2012, 124, 12687-12691.
- Designated a ‘hot paper’ by the editors of Angewandte Chemie
- Inside cover highlight, Angewandte Chemie 2012, 124, 12546
Biomimetic Synthesis of Cbz-(S)-Dolaphenine
Garcia-Reynaga, P.; VanNieuwenhze, M. S., Tetrahedron Lett. 2012, 53, 4989-4993.
Design and Synthesis of a Stable Oxidized Phospholipid Mimic with Specific Binding Recognition for Macrophage Scavenger Receptors
Turner, W. W.; Hartvigsen, K.; Boullier, A.; Montano, E. N.; Witztum, J.; VanNieuwenhze, M. S., J. Med. Chem. 2012, 55, 8178-8182.
Solid-Phase Synthesis of Lysobactin (Katanosin B): Insights into Structure and Function
Hall, E. A.; Kuru, E.; VanNieuwenhze, M. S., Org. Lett. 2012, 14, 2730-2733.
A Model Study for Construction of the DEF-Benzoxocin Ring System of Nogalamycin via Reductive Heck Cyclization
Peng, R.; VanNieuwenhze, M. S., Org. Lett. 2012, 14, 1962-1965.
Synthesis of the AviMeCys-Containing D-Ring of Mersacidin
Carrillo, A. K.; VanNieuwenhze, M. S., Org. Lett. 2012, 14, 1034-1037.
- Manuscript selected for inclusion in a 2012 JACS Select Issue on Peptide Chemistry that highlights noteworthy research in peptide chemistry from Organic Letters, The Journal of Organic Chemistry, and The Journal of the American Chemical Society.
Decarbonylative Approach to the Synthesis of Enamides from Amino Acids: Stereoselective Synthesis of the (S)-(Z)-Aminovinyl–D-Cysteine Unit of Mersacidin
Garcia-Reynaga, P.; Carrillo, A. K.; VanNieuwenhze, M. S., Org. Lett. 2012, 14, 1030-1033.
Synthetic Studies toward the Mannopeptimycins: Synthesis of Orthogonally Protected ß-Hydroxyenduracididines
Olivier, K. S.; VanNieuwenhze, M. S., Org. Lett. 2010, 12, 1680-1683.
Characterization of Oxidized Phosphatidylethanolamine Derived from RAW 264.7 Cells using 4-(Dimethylamino)benzoic Acid Derivatives
Zemski Berry, K. A.; Turner, W. W.; VanNieuwenhze, M. S.; Murphy, R. C., Eur. J. Mass Spectrom. 2010, 16, 463-470.
Stable Isotope Labeled 4-(Dimethylamino) benzoic Acid Derivatives of Glycerophosphoethanolamine Lipids
Zemski Berry, K. A.; Turner, W. W.; VanNieuwenhze, M. S.; Murphy, R. C., Anal. Chem. 2009, 81, 6633-6640.
Small Molecule Detection by Reflective Interferometric Fourier Transform Spectroscopy (RIFTS)
Pacholski, C.; Perelman, L. A.; VanNieuwenhze, M. S.; Sailor, M. J., Phys. Stat. Sol. (a), 2009, 206, 1318-1321
A New Total Synthesis of Patellamide A
Garcia-Reynaga, P.; VanNieuwenhze, M. S., Org. Lett. 2008, 10, 4621-4623.
pH-Triggered Release of Vancomycin from Protein-Capped Porous Films
Perelman, L. A.; Pacholski, C.; Li, Y. Y.; VanNieuwenhze, M. S.; Sailor, M. J., Nanomedicine 2008, 3, 1, 31-43.
Total Synthesis of Plusbacin A3: A Depsipeptide Antibiotic Active Against Vancomycin-Resistant Bacteria
Wohlrab, A.; Lamer, R.; VanNieuwenhze, M. S., J. Am. Chem. Soc. 2007, 129, 4175-4177.
Total Synthesis of Lysobactin
Guzmán-Martínez, A.; Lamer, R.; Narayan, R. S.; VanNieuwenhze, M. S., J. Am. Chem. Soc. 2007, 129, 6017-6021.
- Highlighted: “Total Syntheses of Lysobactin (Katanosin B),” Chem. Intl Ed. 2007, 46, 8548-8552.
Synthesis of Substrates and Biochemical Probes for Study of the Peptidoglycan Biosynthetic Pathway
Narayan, R. S.; VanNieuwenhze, M. S., Eur. J. Org. Chem. 2007, 1399-1414.
A Simplified Biomolecule Attachment Strategy for Biosensing using a Porous Si Oxide Interferometer
Perelman, L. A.; Schwarz, M. P.; Wohlrab, A. VanNieuwenhze, M. S.; Sailor, M. J., Phys. Stat. Sol. (a) 2007, 204, 5, 1394-1398.
An Operationally Simple and Efficient Synthesis of Orthogonally Protected L-threo-ß-Hydroxyasparagine
Guzmán-Martínez, A.; VanNieuwenhze, M. S., Synlett 2007, 1513-1516.
Versatile and Stereoselective Syntheses of Orthogonally Protected ß-Methylcysteine and ß-Methyllanthionine
Narayan, R. S.; VanNieuwenhze, M. S., Org. Lett. 2005, 7, 2655-2658.ß
A Comprehensive Classification System for Lipids
Fahy, E.; Subramaniam, S.; Brown, H. A.; Glass, C. K.; Merrill, Jr, A. H.; Murphy, R. C.; Raetz, C. R. H.; Russell, D. W.; Seyama, Y.; Shaw, W.; Shimizu, T.; Spener, F.; van Meer, G.; VanNieuwenhze, M. S., White, S. H.; Witztum, J. L.; Dennis, E. A., J. Lipid Res. 2005, 46, 839-861.
The First Total Synthesis of Lipid II: The Final Monomeric Intermediate in Bacterial Cell Wall Biosynthesis
VanNieuwenhze, M. S.; Mauldin, S. C.; Zia-Ebrahimi, M. S.; Winger, B. E.; Hornback, W. J.; Saha, S. L.; Dingess-Hammond, E.; Blaszczak, L. C., J. Am. Chem. Soc. 2002, 124, 3656-3660.
An NMR Method for Assigning Relative Stereochemistry to ß-Hydroxy Ketones Deriving from Aldol Reactions of Methyl Ketones
Roush, W. R.; Bannister, T. D.; Wendt, M. D.; VanNieuwenhze, M. S.; Gustin, D. J.; Dilley, G. J.; Lane, G. C.; Scheidt, K.A.; Smith, III, W. J., J. Org. Chem. 2002, 67, 4284-4289.
The Total Synthesis of Lipid I
VanNieuwenhze, M. S.; Mauldin, S. C.; Zia-Ebrahimi, M. S.; Aikins, J. A.; Blaszczak, L. C., J. Am. Chem. Soc. 2001, 123, 6983-6988.
Synthesis of an Orthogonally Protected Precursor to the Glycan Repeating Unit of Bacterial Cell Wall
Saha, S. L.; VanNieuwenhze, M. S.; Hornback, W. J.; Aikins, J.A.; Blaszczak, L. C., Org. Lett. 2001, 3, 3575-3577.
Synthesis of the C (3)-C (15) Segment of Rutamycin B via a C (8)-C (9) Fragment Assembly Aldol Reaction: Metal Dependence of the Aldehyde and Enolate Diastereofacial Selectivities
Gustin, D. J.; VanNieuwenhze, M. S.; Roush, W. R., Tetrahedron Lett. 1995, 36, 3447-3450.
Diastereoselective Aldol Reactions of Chiral Aldehydes and Chiral Methyl Ketones: Dependence of Stereoselectivity on the Metal Enolate, the Aldehyde 2, 3-Stereochemistry, and the Aldehyde ß-Alkoxy Protecting Group
Gustin, D. J.; VanNieuwenhze, M. S.; Roush, W. R., Tetrahedron Lett. 1995, 36, 3443-3446.
Catalytic Asymmetric Dihydroxylation
Kolb, H. C.; VanNieuwenhze, M. S.; Sharpless, K. B., Chem. Rev. 1994, 94, 2483-2547.
The Asymmetric Dihydroxylation of cis-Allylic and Homoallylic Alcohols
VanNieuwenhze, M. S.; Sharpless, K. B., Tetrahedron Lett. 1994, 35, 843-846.
![(Z)-γ-[(Diisopropyl-α-D-mannopyranosyl)oxy]allylstannane: A New Chiral Reagent for the Asymmetric α-Hydroxyallylation of Aldehydes](https://msv.lab.indiana.edu/wp-content/uploads/2018/08/ja00098a014.fp_.png_v03.png)
(Z)-γ-[(Diisopropyl-α-D-mannopyranosyl)oxy]allylstannane: A New Chiral Reagent for the Asymmetric α-Hydroxyallylation of Aldehydes
VanNieuwenhze, M. S.; Roush, W. R., J. Am. Chem. Soc. 1994, 116, 8536-8543.
Kinetic Resolution of Racemic Olefins via Asymmetric Dihydroxylation
VanNieuwenhze, M. S.; Sharpless, K. B., J. Am. Chem. Soc. 1993, 115, 7864-7865.
Synthesis and Structure-Activity Relationships of a Novel Series Non-Peptide Angiotensin II Receptor Binding Inhibitors Specific for the AT2 Subtype
Blankley, C. J., Hodges, J. C., Klutchko, S. R., Himmelsbach, R. J., Chucholowski, A., Connolly, C. J., Neergaard, S. J., VanNieuwenhze, M. S., Sebastian, A., Quin, J. III, Essenburg, A. D., Cohen, D. M., J. Med. Chem. 1991, 34, 3248-3260.
A Stereochemically General Synthesis of 2-Deoxyhexoses via the Asymmetric Allylboration of 2, 3-Epoxyaldehydes.
Roush, W. R., Straub, J. A., VanNieuwenhze, M. S., J. Org Chem. 1991, 56, 1636-1648.
Identification of a trans-Dominant Mutation Affecting Proline Dehydrogenase in Escherichia Coli.
Deutch, C. E., O'Brien, J. M., VanNieuwenhze, M. S., Can. J. Microbiol. 1985, 31, 988-993.
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