The VanNieuwenhze Group

Education

M.S. Biological Sciences – University of Wisconsin-Milwaukee (1994)

B.S. Biological Sciences – University of Wisconsin-Milwaukee (1986)

Research Focus

Mechanism of antibiotics and natural products that inhibit peptidoglycan synthesis and their role in lipid recycling

Publications/Patents

• MicrobeJ, a tool for high throughput bacterial cell detection and quantitative analysis. Nature Microbiology, 1(7), 16077-16083.
• Phosphate Flow between Hybrid Histidine Kinases CheA₃and CheS₃ Controls Rhodospirillum centenum Cyst Formation. PLoS Genet 2013, 9, e1004002.

• Surface contact stimulates the just‐in‐time deployment of bacterial adhesins. Mol. Microbiol. 2012, 83, 41-51.

• Mutations in DivL and CckA Rescue a divJ Null Mutant of Caulobacter crescentus by Reducing the Activity of CtrA. J. Bacteriol. 2006, 188, 2473-82.

• Cell cycle timing and developmental checkpoints in Caulobacter crescentus. Curr Opin Microbiol 2003, 6, 541-9.

• Proteomic analysis of the Caulobacter crescentus stalk indicates competence for nutrient uptake. Mol. Microbiol. 2002, 45, 1029-41.

• DNA replication initiation is required for mid‐cell positioning of FtsZ rings in Caulobacter crescentus. Mol. Microbiol. 2002, 45, 605-16.

• Cell cycle and positional constraints on FtsZ localization and the initiation of cell division in Caulobacter crescentus. Mol. Microbiol. 2001, 39, 949-59.

• Regulation of Stalk Elongation by Phosphate in Caulobacter crescentus. J. Bacteriol. 2000, 182, 337-47.

• Dominant C‐terminal deletions of FtsZ that affect its ability to localize in Caulobacter and its interaction with FtsA. Mol. Microbiol. 1998, 27, 1051-63.

• Cell cycle-dependent transcriptional and proteolytic regulation of FtsZ in Caulobacter. Genes Dev 1998, 12, 880-93.

• Morphological adaptation and inhibition of cell division during stationary phase in Caulobacter crescentus. Mol. Microbiol. 1998, 29, 963-73.

• Cell cycle regulation and cell type-specific localization of the FtsZ division initiation protein in Caulobacter. Proc Natl Acad Sci U S A 1996, 93, 6314-9.

• Use of 7-alkoxyphenoxazones, 7-alkoxycoumarins and 7-alkoxyquinolines as fluorescent substrates for rainbow trout hepatic microsomes after treatment with various inducers. Biochem. Pharmacol. 1994, 47, 893-903.

• Hepatic CYP1A1 Induction in Rainbow Trout by Continuous Flowthrough Exposure to β-Naphthoflavone. Fundam. Appl. Toxicol. 1993, 20, 72-82.

• CYP1A1 protein and mRNA in teleosts as an environmental bioindicator: laboratory and environmental studies. Marine Environmental Research 1992, 34, 139-145.